| product Name | TOREMIFENE CITRATE |
|---|---|
| Synonyms | (z)-4-chloro-1,2-diphenyl-1-(4-(2-(n,n-dimethylamino)ethoxy)phenyl)-1-butene ; 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin ; 2-hydroxy-1,2,3-propanetricarboxylate(1:1) ; fareston ; fc1157a ; nk622 ; ; (z)-2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethyl-ethanamine 2-hydroxy-1,2,3-propanetricarboxylate ; TROPISETRON CITRATE ; 2-[4-[(1Z)-4-CHLORO-1,2-DIPHENYL-1-BUTENYL]PHENOXY]-N,N-DIMETHYLETHANAMINE; |
| Molecular Formula | C26H28ClNO・C6H8O7 |
| Molecular Weight | 598.09 |
| InChI | InChI=1/C26H28ClNO.C6H8O7/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-16H,17-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-; |
| CAS Registry Number | 89778-27-8 |
| Molecular Structure | 
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| Description | Toremifene (citrate) is an orally bioavailable selective estrogen receptor modulator (SERM) that evokes tissue-dependent effects similar to that of tamoxifen . It has been shown to block estrogen-stimulated growth of MCF-7 breast cancer cells grown in tissue culture, to inhibit ovariectomy-induced bone loss in rats, and to stimulate endometrial growth similar to that of tamoxifen. |
| Chemical Properties | Chemical Properties |
| Uses | 1.An antiestrogen and antineoplastic. Nonsteroidal antiestrogen structurally similar to Tamoxifen. 2.anesthetic 3.Toremifene citrate salt has been used: ● in cell-based ELISA ● as a positive control to detect its antiviral activity against Ebola virus (EBOV) ● to treat MCF7 and T47D breast cancer cell lines |
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