| product Name |
3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate |
| Synonyms |
3,4-Dihydro-4-oxo-6-acetoxy-7-methoxyquinazoline; 6-(Acetyloxy)-7-methoxy-4(3H)-quinazolinone; 7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate; 6-Acetoxy-7-methoxy-4(3H)-quinazolinone; 6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4(3H)-one; (7-methoxy-4-oxo-1H-quinazolin-6-yl) acetate; 6-acetoxy-7-methoxy-3,4-dihydroquizolin-4-one |
| Molecular Formula |
C11H10N2O4 |
| Molecular Weight |
234.2081 |
| InChI |
InChI=1/C11H10N2O4/c1-6(14)17-10-3-7-8(4-9(10)16-2)12-5-13-11(7)15/h3-5H,1-2H3,(H,12,13,15) |
| CAS Registry Number |
179688-53-0 |
| Molecular Structure |
|
| Density |
1.395g/cm3 |
| Boiling point |
452.391°C at 760 mmHg |
| Refractive index |
1.612 |
| Flash point |
227.398°C |
| Vapour Pressur |
0mmHg at 25°C |
| Chemical Properties |
Brown solid powder |
| Uses |
4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid exhibit potent inhibitory activity against VEGFR-2/HDAC and a human breast cancer cell line MCF-7. |
| Preparation Products |
Poziotinib (HM781-36B)–>6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one–>4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol–>6-Quinazolinol, 4-chloro-7-methoxy—>6-Acetoxy-4-chloro-7-methoxyquinazoline–>6-Quinazolinol, 4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate |
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