| product Name |
trans-4-Dimethylaminocrotonic acid hydrochloride |
| Synonyms |
(E)-4-(Dimethylamino)-2-butenoic acid hydrochloride; (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride (1:1); trans-4-N,N-dimethylainocrotonic acid hydrochloride; (E)-4-(Dimethylamino)But-2-Enoic Acid Hydrochloride; trans-4-Dimethylaminocrotonic acid HCL; (2E)-4-(dimethylamino)-2-butenoic acid,hydrochloride |
| Molecular Formula |
C6H12ClNO2 |
| Molecular Weight |
165.61798 |
| InChI |
InChI=1/C6H11NO2.ClH/c1-7(2)5-3-4-6(8)9;/h3-4H,5H2,1-2H3,(H,8,9);1H/b4-3+; |
| CAS Registry Number |
848133-35-7 |
| Molecular Structure |
|
| Description |
trans-4-Dimethylaminocrotonic acid hydrochloride is a very important pharmaceutical intermediate and is an essential part of the structure of the anti-tumour drugs afatinib and neratinib. It is also an important organic synthesis reagent for the preparation of novel pyrazole derivatives and 6-heterocycloalkyl quinazoline derivatives. |
| Chemical Properties |
White Solid |
| Uses |
trans 4-Dimethylaminocrotonic acid HCl is a reagent used in the preparation of tyrosine kinase inhibiting antitumor agents. |
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