| product Name |
4-Methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline |
| Synonyms |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine; 4-Methyl-N’-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine; N-(5-amino-2-methylphenyl)-4-(3-pyrdyl)-2-pydimidineamine; N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine; N-(5-amino-2-methylphenl)-4-(3-pyridyl)-2-pyrimidine-amine; 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine; 4-methyl-N~3~-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine; 6-methyl-N’-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine; N-(2-methyl-5-aminophenyl)-4-(3-pyridyl)-2-pyrimidine amine; N-(2-Methyl-5-Amino Phenyl)-4-(3-Pyridyl)-2-Pyrimidine; 2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine |
| Molecular Formula |
C16H15N5 |
| Molecular Weight |
277.3238 |
| InChI |
InChI=1/C16H15N5/c1-11-4-5-13(17)9-15(11)21-16-19-8-6-14(20-16)12-3-2-7-18-10-12/h2-10H,17H2,1H3,(H,19,20,21) |
| CAS Registry Number |
152460-10-1 |
| Molecular Structure |
![152460-10-1 4-Methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline](https://images-a.chemnet.com/suppliers/chembase/948/293948.gif)
|
| Density |
1.266g/cm3 |
| Boiling point |
537.325°C at 760 mmHg |
| Refractive index |
1.688 |
| Flash point |
278.765°C |
| Vapour Pressur |
0mmHg at 25°C |
| Description |
4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib. |
| Chemical Properties |
Pale-Yellow Solid |
| Uses |
4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis. |
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