| product Name |
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline |
| Synonyms |
1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole; 3-(trifluoromethyl)-5-(4-methyl-1H-imidazol-1-yl)benzenamine; 3-(4-Methyl-imidazole-1-yl)-5-trifluoro methylphenylamine; 3-(4-Methyl-imidazol-1-yl)-5-trifluoro-methylphenylamine |
| Molecular Formula |
C11H10F3N3 |
| Molecular Weight |
241.2124 |
| InChI |
InChI=1/C11H10F3N3/c1-7-5-17(6-16-7)10-3-8(11(12,13)14)2-9(15)4-10/h2-6H,15H2,1H3 |
| CAS Registry Number |
641571-11-1 |
| Molecular Structure |
|
| Density |
1.354g/cm3 |
| Boiling point |
379.805°C at 760 mmHg |
| Refractive index |
1.553 |
| Flash point |
183.5°C |
| Vapour Pressur |
0mmHg at 25°C |
| Description |
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline is a pharmaceutical intermediate component used in the preparation of Nilotinib for the treatment of a variety of leukaemias, including chronic myeloid leukaemia (CML). |
| Chemical Properties |
es 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline is a white to light grey to light yellow powder to crystals with a melting point of 130 °C. |
| Uses |
Intermediate in the preparation of Nilotinib. |
Reviews
There are no reviews yet.