| product Name |
5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde |
| Synonyms |
5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde; [5-[4-[4-[(3-Fluorobenzyl)oxy]-3-chloroanilino]-6-quinazolinyl]-2-furancarboxaldehyde; 5-[4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)quinazolin-6-yl]furan-2-carbaldehyde; 5-(4-(3-Chloro-4-((3-fluorobenzyloxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde; 5-[4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)quinazolin-6-yl]-2-furaldehyde; Lapatinib Intermediate 3; 5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)-2-furaldehyde; 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy] phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde |
| Molecular Formula |
C26H17ClFN3O3 |
| Molecular Weight |
473.8829 |
| InChI |
InChI=1/C26H17ClFN3O3/c27-22-12-19(5-8-25(22)33-14-16-2-1-3-18(28)10-16)31-26-21-11-17(4-7-23(21)29-15-30-26)24-9-6-20(13-32)34-24/h1-13,15H,14H2,(H,29,30,31) |
| CAS Registry Number |
231278-84-5 |
| Molecular Structure |
![231278-84-5 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde](https://images-a.chemnet.com/suppliers/chembase/373/373445_1.gif)
|
| Density |
1.407g/cm3 |
| Boiling point |
650.3°C at 760 mmHg |
| Refractive index |
1.694 |
| Flash point |
347.1°C |
| Vapour Pressur |
8.52E-17mmHg at 25°C |
| Chemical Properties |
Dark Brown Solid |
| Uses |
Lapatinib intermediate. |
| Raw materials |
5-Formylfuran-2-boronic acid, pinacol ester–>N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine–>2-Formylfuran-5-boronic acid–>N-(3-Chloro-4-(3-fluorobenzyloxy)phenyl)-6-iodoquinazolin-4-aMine drochloride–>6-Bromo-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine–>5-Formylfuran-2-boronic acid, neopentyl glycol ester |
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