Alogliptin Benzoate APIs

Factory Supply 874638-80-9 | ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate factory price

Categories: Other intermediates, Pharmaceutical Intermediates Tags: Anti-virals intermediates, Saufosbuvir intermediates

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product Name	((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
Synonyms	(2R,3R,4R)-3-(benzoyoxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2yl)methyl Benzoate; D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, γ-lactone, 3,5-dibenzoate, (2R)-; (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate; ((2R,3R,4R)-3-(Benzoyloxy)-4-Fluoro-4-Methyl-5-Oxotetrahydrofuran-2-Yl) Methyl Benzoate; [(2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetra-2-yl)methyl benzoate; 3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribono-Y-lactone; ((2R,3R,4R)-3-benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate; 3,5-dibenzoate-(2R)-2-deoxy-2-fluoro-2-methyl-D-erythro-Pentonic acid, γ-lactone; (2R)-2-Deoxy-2-fluoro-2-methy-D- erythropentonic acid gamma-lactone 3,5- dibenzoate
Molecular Formula	C₂₀H₁₇O₆F
Molecular Weight	372.3497
CAS Registry Number	874638-80-9
Molecular Structure
Uses	1.neuromuscular blocking agent 2.(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1”-C-cyano-2”-fluoro-2”-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
Application	((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate is an impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.
Raw materials	D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester–>(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one–>Benzoyl chloride

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