| product Name |
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one |
| Synonyms |
7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one; 7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(3H)-quinazolinone; 7-methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one; 7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3h)-one; 7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one |
| Molecular Formula |
C16H21N3O4 |
| Molecular Weight |
319.3556 |
| InChI |
InChI=1/C16H21N3O4/c1-21-14-10-13-12(16(20)18-11-17-13)9-15(14)23-6-2-3-19-4-7-22-8-5-19/h9-11H,2-8H2,1H3,(H,17,18,20) |
| CAS Registry Number |
199327-61-2 |
| Molecular Structure |
|
| Density |
1.327g/cm3 |
| Boiling point |
519.53°C at 760 mmHg |
| Refractive index |
1.611 |
| Flash point |
268.002°C |
| Vapour Pressur |
0mmHg at 25°C |
| Description |
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells. |
| Chemical Properties |
White Solid |
| Uses |
Gefitinib intermediate. |
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