Chemical Intermediate 915095-89-5 | (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan

product Name	(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan
Synonyms	(3s)-3-(4-((5-bromo-2-chlorophenyl)methyl)phenoxy)tetrahydro-furan; (3S)-3-(4-(5-bromo-2-chlorobenzyl) methyl]phenoxy]tetrahydro-furan
Molecular Formula	C₁₇H₁₆BrClO₂
Molecular Weight	367.66
CAS Registry Number	915095-89-5
Molecular Structure
Description	(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant to efficiently synthesize SGLT- 2 Epagliflozin inhibitors.
Uses	(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.
Raw materials	(5-broMo-2-chlorophenyl)(4-hydroxyphenyl)Methanone–>(R)-(-)-3-Hydroxytetrahydrofuran–>5-BROMO-2-CHLORO-BENZOYL CHLORIDE–>(S)-(5-broMo-2-chlorophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)Methanone–>(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone–>4-bromo-2-(bromomethyl)-1-chlorobenzene–>4-(5-broMo-2-chlorobenzyl)phenol–>5-Bromo-2-chlorobenzoic acid–>(S)-(+)-3-Hydroxytetrahydrofuran–>4-Bromoaniline–>Fluorobenzene–>p-Fluorotoluene

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