Excellent chemical intermediates 3094-09-5 | Doxifluridine

product Name Doxifluridine
Synonyms 5′-Deoxy-5-fluorouridine; 5′-DFUR; (2xi)-5′-deoxy-5-fluorouridine; 5-Fluoro-5′-deoxyuridine
Molecular Formula C9H11FN2O5
Molecular Weight 246.1924
InChI InChI=1/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6?,8?/m1/s1
CAS Registry Number 3094-09-5
EINECS 221-440-1
Molecular Structure 3094-09-5 Doxifluridine

Density 1.63g/cm3
Refractive index 1.605
Hazard Symbols
Description Doxifluridine is a prodrug derivative of 5-fluorouracil (5-FU). As an antineoplastic it is more potent than 5-FU in the treatment of breast, stomach, colon and rectal cancers.
Uses 1. A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity
2. An antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. A metabolite of Capecitabine
3. 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.
4. antineoplastic, pyrimidine antimetabolite

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