Pharmaceutical Intermediate 1132832-75-7 | Methanone, (5-Bromo-2-methylphenyl)[5-(4-fluorophenyl)-2-thienyl]- Jinjiang X Pharmaceutical Co.,Ltd

product Name	Methanone, (5-Bromo-2-methylphenyl)[5-(4-fluorophenyl)-2-thienyl]-
Synonyms	(5-bromo-2-methylphenyl)-(5-(4-fluorophenyl)-2-thienyl)methanone; 2-(5-Bromo-2-Methylbenzoyl)-5-(4-Fluorophenyl)Thiophene; (5-broMo-2-Methylphenyl)(5-(4-fluorophenyl)thiophen-2-yl)Methanone
Molecular Formula	C₁₈H₁₂BrFOS
Molecular Weight	375.25
CAS Registry Number	1132832-75-7
Molecular Structure
Uses	2-(5-Bromo-2-methylbenzoyl)-5-(4-fluorophenyl)thiophene is an intermediate in the preparation of Canagliflozin which is a sodium-dependent glucose co-transporter 2 inhibitor used in the treatment of type 2 diabetes.
Raw materials	2-Bromo-5-(4-fluorophenyl)thiophene–>5-bromo-N-methoxy-N,2-dimethylbenzamide–>5-(4-Fluorophenyl)thiophene-2-carboxaldehyde–>2-(4-Fluorophenyl)-thiophene–>5-(4-Fluorophenyl)thiophene-2-carboxylic acid–>5-Bromo-2-methylbenzoyl chloride–>5-Bromo-2-methylbenzoic acid–>3-(4-FLUOROBENZOYL)PROPIONIC ACID–>4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE–>4-Bromotoluene–>Fluorobenzene–>2-Thiophenecarboxaldehyde–>4-Fluorobenzeneboronic acid–>4-Bromofluorobenzene

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